Please use this identifier to cite or link to this item: http://idr.nitk.ac.in/jspui/handle/123456789/10359
Full metadata record
DC FieldValueLanguage
dc.contributor.authorBhat, S.I.-
dc.contributor.authorChoudhury, A.R.-
dc.contributor.authorTrivedi, D.R.-
dc.date.accessioned2020-03-31T08:19:00Z-
dc.date.available2020-03-31T08:19:00Z-
dc.date.issued2012-
dc.identifier.citationRSC Advances, 2012, Vol.2, 28, pp.10556-10563en_US
dc.identifier.urihttp://idr.nitk.ac.in/jspui/handle/123456789/10359-
dc.description.abstractThe reaction of malononitrile with salicylaldehyde under solvent and catalyst free conditions was re-investigated using mechanochemical mixing, thermal heating and a direct crystallization process. The resulting condensation product by all three types of molecular activation, was found to be (2-amino-3-cyano-4H-chromene-4-yl)malononitrile, which is not the previously reported benzofuran-2-carbonitrile. The structure of the resulting chromene derivative was confirmed by FT-IR, MS, 1H, 13C NMR and single crystal and powder X-ray diffraction. The reaction pathway under neat conditions (mechanochemical mixing) at ambient temperature was monitored by IR spectral measurements. The versatility of the current green protocol was examined through the reaction of eleven derivatives of o-hydroxybenzaldehyde with malononitrile to obtain 2-amino-3-cyano-4H-chromene derivatives. In addition, malononitrile was further reacted with o-aminobenzaldehydes under neat conditions to yield quinoline derivatives. 2012 The Royal Society of Chemistry.en_US
dc.titleCondensation of malononitrile with salicylaldehydes and o-aminobenzaldehydes revisited: Solvent and catalyst free synthesis of 4H-chromenes and quinolinesen_US
dc.typeArticleen_US
Appears in Collections:1. Journal Articles

Files in This Item:
File Description SizeFormat 
10359.pdf568.71 kBAdobe PDFThumbnail
View/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.