Please use this identifier to cite or link to this item: http://idr.nitk.ac.in/jspui/handle/123456789/12225
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dc.contributor.authorVijesh, A.M.
dc.contributor.authorIsloor, A.M.
dc.contributor.authorShetty, P.
dc.contributor.authorSundershan, S.
dc.contributor.authorFun, H.K.
dc.date.accessioned2020-03-31T08:38:49Z-
dc.date.available2020-03-31T08:38:49Z-
dc.date.issued2013
dc.identifier.citationEuropean Journal of Medicinal Chemistry, 2013, Vol.62, , pp.410-415en_US
dc.identifier.urihttp://idr.nitk.ac.in/jspui/handle/123456789/12225-
dc.description.abstractAzole class of compounds are well known for their excellent therapeutic properties. Present paper describes about the synthesis of three series of new 1,2,4-triazole and benzoxazole derivatives containing substituted pyrazole moiety (11a-d, 12a-d and 13a-d). The newly synthesized compounds were characterized by spectral studies and also by C, H, N analyses. All the synthesized compounds were screened for their analgesic activity by the tail flick method. The antimicrobial activity of the new derivatives was also performed by Minimum Inhibitory Concentration (MIC) by the serial dilution method. The results revealed that the compound 11c having 2,5-dichlorothiophene substituent on pyrazole moiety and a triazole ring showed significant analgesic and antimicrobial activity. 2012 Elsevier Masson SAS. All rights reserved.en_US
dc.titleNew pyrazole derivatives containing 1,2,4-triazoles and benzoxazoles as potent antimicrobial and analgesic agentsen_US
dc.typeArticleen_US
Appears in Collections:1. Journal Articles

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