Please use this identifier to cite or link to this item: http://idr.nitk.ac.in/jspui/handle/123456789/13209
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dc.contributor.authorChandrakantha, B.
dc.contributor.authorIsloor, A.M.
dc.contributor.authorShetty, P.
dc.contributor.authorFun, H.K.
dc.contributor.authorHegde, G.
dc.date.accessioned2020-03-31T08:45:23Z-
dc.date.available2020-03-31T08:45:23Z-
dc.date.issued2014
dc.identifier.citationEuropean Journal of Medicinal Chemistry, 2014, Vol.71, , pp.316-323en_US
dc.identifier.urihttp://idr.nitk.ac.in/jspui/handle/123456789/13209-
dc.description.abstractA new series of N-[5-(4-(alkyl/aryl)-3-nitro-phenyl)-[1,3,4-thiadiazol-2- yl]-2,2-dimethyl-propionamide 4 (a-l) and 6-(4-Methoxy-phenyl)-2-(4-alkyl/aryl)- 3-nitro-phenyl)-Imidazo [2,1-b] [1,3,4] thiadiazole 6 (a-l) were synthesized starting from 5-(4-Fluoro-3-nitro-phenyl)-[1,3,4] thiadiazole-2-ylamine. The synthesized compounds were characterized by IR, NMR, mass spectral and elemental analysis. All the compounds were tested for antibacterial and antifungal activities. The antimicrobial activities of the compounds were assessed by well plate method (zone of inhibition). Compounds 4a, 4c and 6e, 6g displayed appreciable activity at the concentration 0.5-1.0 mg/mL. 2013 Elsevier Masson SAS. All rights reserved.en_US
dc.titleSynthesis and biological evaluation of novel substituted 1,3,4-thiadiazole and 2,6-di aryl substituted imidazo [2,1-b] [1,3,4] thiadiazole derivativesen_US
dc.typeArticleen_US
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