Please use this identifier to cite or link to this item: http://idr.nitk.ac.in/jspui/handle/123456789/13291
Full metadata record
DC FieldValueLanguage
dc.contributor.authorGarudachari, B.-
dc.contributor.authorIsloor, A.M.-
dc.contributor.authorSatyanarayan, M.N.-
dc.contributor.authorAnanda, K.-
dc.contributor.authorFun, H.-K.-
dc.date.accessioned2020-03-31T08:45:32Z-
dc.date.available2020-03-31T08:45:32Z-
dc.date.issued2014-
dc.identifier.citationRSC Advances, 2014, Vol.4, 58, pp.30864-30875en_US
dc.identifier.urihttps://idr.nitk.ac.in/jspui/handle/123456789/13291-
dc.description.abstractThe present paper describes the synthesis of two new series of 7-(trifluoromethyl)-4-hydroxy substituted quinoline carbohydrazide derivatives (6a-e and 7a-g) and N-alkyl-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7- (trifluoromethyl) quinolin-4-amine derivatives (9a-f). Newly synthesized compounds were characterized by spectral studies. The structure of 9a was evidenced by X-ray crystallographic study. Synthesized compounds were screened for their antibacterial performance against Mycobacterium smegmatis and Pseudomonas aeruginosa. Antifungal activity was also carried out on the fungal stains Candida albicans and Penicillium chrysogenum. Compounds 7a and 9c showed significant antimicrobial activity against all the tested microorganisms. Among all the compounds, 6d and 6e showed the lowest MIC value of 6.25 ?g mL -1 against Mycobacterium smegmatis indicating these compounds can be possible future antituberculosis agents. 2014 the Partner Organisations.en_US
dc.titleSynthesis, characterization and antimicrobial studies of some new trifluoromethyl quinoline-3-carbohydrazide and 1,3,4-oxadiazolesen_US
dc.typeArticleen_US
Appears in Collections:1. Journal Articles

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.