6-(4-Bromophenyl)-2-eth-oxy-4-(2,4,5-trimethoxyphenyl)nicotinonitrile

Abstract

There are two mol-ecules in the asymmetric unit of the title compound, C23H21BrN2O4, which differ in the conformation of their ethoxy residues, i.e. almost co-planar with the pyridine ring in one mol-ecule [C - O - C - C = -174.0 (2) ] but almost perpendicular in the other [C - O - C - C = 92.8 (3) ]. The dihedral angles between the central pyridine ring and the 4-bromo-phenyl and 2,4,5-trimethoxy-phenyl rings are 11.05 (12) and 63.78 (12) , respectively, in one mol-ecule; the corres-ponding angles in the other mol-ecule are 30.38 (13) and 65.38 (13) , respectively. In the crystal structure, pairs of mol-ecules are arranged in a face-to-face sandwich structure which further stacks along the b axis. The crystal packing features C - H?? inter-actions and Br?O [3.5417 (17) ], Br?C [3.748 (3) ], C?N [3.376 (4) ] and C?O [3.351 (3)-3.409 (3) ] contacts. Finally, ??? inter-actions [centroid?centroid distances = 3.6346 (19) and 3.6882 (19) ] are observed.